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Laboratorio di Immunità adattativa

Attività di Ricerca Antonella Viola Pubblicazioni
PUBBLICAZIONI SELEZIONATE

  1. A. Viola & A. Lanzavecchia. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science , 273:104.
  2. A. Viola, M. Salio, L. Tuosto, S. Linkert, O. Acuto & A. Lanzavecchia. 1997. Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering. The Journal of Experimental Medicine, 186:1775.
  3. A. Viola, S. Schroeder, Y. Sakakibara &. A. Lanzavecchia. 1999. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science , 283: 680.
  4. M. F. Bachmann, A. Gallimore, S. Linkert, V. Cerundolo, A. Lanzavecchia, M. Kopf & A. Viola. 1999. Developmental regulation of Lck-targeting to the CD8 coreceptor controls signaling in naive and memory T cells. The Journal of Experimental Medicine, 189: 1521-9.
  5. A. Viola. 2001. Amplification of TCR signaling by membrane dynamic microdomains. Trends in Immunology , 22:322-7.

  6. R. Zambello, A. Cabrelle, L. Trentin, C. Agostini, G. Semenzato and A. Viola. 2004. The raft marker GM1 distinguishes functional subsets of Granular Lymphocytes in patients with CD3 Lymphoproliferative Disease of Granular Lymphocytes. Leukemia, 18:771-6.

  7. V. Bronte, T. Kasic, G. Gri, K. Gallana, G. Borsellino, I. Marigo, L. Battistini, M. Iafrate, T. Prayer-Galetti, F. Pagano and A. Viola. 2005. Boosting anti-tumor responses of T lymphocytes infiltrating human prostate cancers. The Journal of Experimental Medicine, 201:1257-68.
  8. B. Molon, G. Gri, M. Bettella, C. Goumez-Mouton, A. Lanzavechia, C. Martinez-A, S. Manes and A. Viola. 2005. T cell costimulation by chemokine receptors. Nature Immunology, 6:465-71 .
  9. A. Viola, R. Contento and B. Molon. 2006. T cells and their partners: the chemokine dating agency. Trends in Immunology, 27:421-427.
  10. R. Tavano, R.L. Contento, S.J. Baranda, M. Soligo, L. Tuosto, S. Manes and A. Viola. 2006. CD28 interaction with filamin-A controls lipid raft accumulation at the T cell immunological synapse. Nature Cell Biology, 8:1270-1276.
  11. S. Campello, R.A. Lacalle, M. Bettella, S. Manes, L. Scorrano and A. Viola. 2006. Orchestration of leukocyte chemotaxis by mitochondrial dynamycs. The Journal of Experimental Medicine, 203: 2879-2886.
  12. A. Viola and N. Gupta. 2007. Tether and Trap: Regulation of membrane rafts by actin-binding proteins. Nature Reviews Immunology, 7:889-96.
  13. A. Viola and A.D. Luster. 2008. Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation. Annual Review of Pharmacology and Toxicology, 48:171-197.
  14. R.L. Contento, B. Molon, C. Boularan, T. Pozzan, S. Manes, S. Marullo and A. Viola. 2008. CXCR4-CCR5: a new couple modulating T-cell functions. Proceedings of the National Academy of Science, in press.

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Autorizzazioni: Decreto Presidente Regione Lombardia n° 1906 del 18.04.1996 Direttore Sanitario: dott. Norberto Silvestri - Specialista in Igiene e Tecnica Ospedaliera. L'Istituto Clinico Humanitas è una struttura ospedaliera accreditata Joint Commission International.